Megumi Goto Selected Research

GPR39-C3

8/2019	G Protein-Coupled Receptor 39 Agonist Improves Concanavalin A-Induced Hepatitis in Mice.
9/2018	G protein-coupled receptor 39 plays an anti-inflammatory role by enhancing IL-10 production from macrophages under inflammatory conditions.

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Megumi Goto Research Topics

Disease

4	Neoplasms (Cancer) 01/2022 - 08/2005
4	Inflammation (Inflammations) 09/2018 - 06/2009
2	Hepatitis 08/2019 - 10/2009
2	Dermatitis 06/2009 - 01/2005
2	Edema (Dropsy) 06/2009 - 05/2006
1	Alzheimer Disease (Alzheimer's Disease) 05/2022
1	Dementia (Dementias) 05/2022
1	Fibrolamellar hepatocellular carcinoma 01/2022
1	Graves Disease (Basedow Disease) 04/2021
1	Thyroiditis 04/2021
1	Scleroatonic muscular dystrophy 01/2021
1	Muscular Diseases (Myopathy) 01/2021
1	Necrosis 08/2019
1	Autoimmune Hepatitis 08/2019
1	Sepsis (Septicemia) 09/2018
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2018
1	Thyroid Diseases (Thyroid Disease) 01/2018
1	Cognitive Dysfunction 09/2017
1	Muscular Atrophy (Muscle Atrophy) 01/2017
1	Weight Loss (Weight Reduction) 01/2017
1	Schizophrenia (Dementia Praecox) 01/2013
1	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 06/2012
1	Human Influenza (Influenza) 04/2011
1	Infections 04/2011
1	Radiation Injuries (Radiation Sickness) 11/2010
1	Wounds and Injuries (Trauma) 11/2010
1	Hyperplasia 05/2010
1	Psoriasis (Pustulosis Palmaris et Plantaris) 05/2010
1	Peritonitis 05/2006
1	Hypereosinophilic Syndrome (Loeffler Endocarditis) 07/2005

Drug/Important Bio-Agent (IBA)

3	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 05/2010 - 06/2009
2	Biomarkers (Surrogate Marker)IBA 05/2022 - 12/2019
2	Amyloid (Amyloid Fibrils)IBA 05/2022 - 09/2017
2	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 08/2019 - 09/2018
2	GPR39-C3IBA 08/2019 - 09/2018
2	Concanavalin AIBA 08/2019 - 10/2009
2	1- cyclohexyl- N- (6- (4- hydroxy- 1- piperidinyl)- 3- pyridinyl)- 3- methyl- 1H- thieno(2,3- c)pyrazole- 5- carboxamideIBA 05/2010 - 06/2009
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2009 - 06/2009
2	Chymases (Chymase)IBA 05/2006 - 07/2005
1	Thyroid HormonesIBA 05/2022
1	Glucose (Dextrose)FDA LinkGeneric 05/2022
1	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA 01/2022
1	HLA-DRB1 Chains (HLA DRB1)IBA 04/2021
1	HLA Antigens (Human Leukocyte Antigens)IBA 04/2021
1	Amino Acids FDA Link 04/2021
1	CollagenIBA 01/2021
1	Alanine Transaminase (SGPT)IBA 08/2019
1	Immunosuppressive Agents (Immunosuppressants)IBA 08/2019
1	Interleukin-10 (Interleukin 10)IBA 09/2018
1	Carboxy-LyasesIBA 01/2018
1	Insulin (Novolin)FDA Link 01/2018
1	AcidsIBA 01/2018
1	Anthocyanins (Anthocyanin)IBA 01/2017
1	delphinidinIBA 01/2017
1	Antipsychotic Agents (Antipsychotics)IBA 01/2013
1	RNA (Ribonucleic Acid)IBA 06/2012
1	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 04/2011
1	Fibroblast Growth Factor 1 (FGF-1)IBA 11/2010
1	Heparin (Liquaemin)FDA LinkGeneric 11/2010
1	Pharmaceutical PreparationsIBA 10/2009
1	Interleukin-4 (Interleukin 4)IBA 10/2009
1	CytokinesIBA 10/2009
1	1- cyclohexyl- N- (3- fluoro- 4- (4- methyl- 1- piperazinyl)phenyl)- 3- methyl- 1H- thieno(2,3- c)pyrazole- 5- carboxamideIBA 10/2009
1	alpha-galactosylceramideIBA 10/2009
1	Phorbol EstersIBA 06/2009
1	mast cell protease 4IBA 05/2006
1	ChemokinesIBA 05/2006
1	Cancer VaccinesIBA 08/2005
1	Proteins (Proteins, Gene)FDA Link 08/2005
1	EpitopesIBA 08/2005
1	DinitrofluorobenzeneIBA 01/2005
1	AntigensIBA 01/2005

Therapy/Procedure

3	Oral Administration 08/2019 - 01/2017
1	Drug Therapy (Chemotherapy) 01/2022
1	Cell Transplantation 01/2021
1	Transplantation 01/2021
1	Immunotherapy 12/2019
1	Intradermal Injections 05/2006